The Deep Desert wipe changes everything
Base location is a weekly decision, not a permanent one: every Tuesday the Deep Desert wipes (sandstorm builds 8–10 hours, wipe at storm peak) and its 81 cells reset. Anything built in the contested interior is exposed to the reset rhythm; the safe anchor is the Shield Wall line along rows A/B.
PvE vs PvP positioning
Rows A–E are PvE zones — build there for uncontested farming. Rows F–I are PvP zones with 2.5x output — build there only if you can defend it and only if you schedule around the weekly wipe. Most solo players are better off PvE-side with a forward PvP outpost if needed.
Economy logistics
Two Exchange terminals exist — Arrakeen and Harko Village — and listing requires you to be physically at the terminal. A base far from both means every trade run is a trip; factor travel time into your location choice, and remember the Exchange is World-wide so your market does not care where in the World you build — only you do.